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. 2015 Sep 22;6(5):e00942-15. doi: 10.1128/mBio.00942-15

TABLE 5 .

C. albicans genes most upregulated during systemic infection

orf19 name Gene name Description Fold change compared to in vitro growth (log2 values)a
Gm, 2 h Gm, 24 h Mm, 16 h Mm, 48 h
orf19.7455 orf19.7455 Ortholog of C. dubliniensis CD36: Cd36_86630 11.38 11.24 11.80 11.60
orf19.1321 HWP1 Hyphal cell wall protein 10.46 9.89 10.63 11.54
orf19.6028 HGC1 Hypha-specific G1 cyclin-related protein involved in
regulation of morphogenesis
9.78 9.55 10.39 11.05
orf19.3374 ECE1 Hypha-specific protein 8.73 9.26 9.40 11.04
orf19.1363 orf19.1363 Putative protein of unknown function 7.85 7.38 8.53 10.45
orf19.5636 RBT5 GPI-linked cell wall protein 6.80 9.50 8.43 9.85
orf19.2060 SOD5 Cu and Zn-containing superoxide dismutase 8.55 6.97 8.43 9.59
orf19.7094 HGT12 Glucose, fructose, mannose transporter 13.09 12.62 8.41 12.76
orf19.1816 ALS3 Cell wall adhesin 8.02 4.20 8.31 8.59
orf19.5585 SAP5 Secreted aspartyl proteinase 8.22 8.57 8.25 10.22
orf19.1822 UME6 Zn(II)2Cys6 transcription factor 7.86 7.86 8.11 8.87
orf19.2457 orf19.2457 Protein of unknown function 9.59 8.99 7.91 8.41
orf19.5952 orf19.5952 Protein of unknown function 3.11 8.13 7.84 8.73
orf19.2062 SOD4 Cu and Zn-containing superoxide dismutase 7.50 9.64 7.71 6.64
orf19.2061 orf19.2061 Ortholog of C. albicans WO-1: CAWG_03846 10.23 6.52 7.56 9.61
orf19.4599 PHO89 Putative phosphate permease 6.87 7.54 7.21 7.20
orf19.1264 CFL2 Oxidoreductase; iron utilization 5.46 8.23 7.08 6.86
orf19.1930 CFL5 Ferric reductase 6.92 12.92 6.96 9.38
orf19.113 CIP1 Possible oxidoreductase 7.88 7.90 6.82 8.31
orf19.6148 orf19.6148 Homolog of nuclear distribution factor NudE, NUDEL 4.84 6.29 6.69 8.66
a

Mm, M. musculus; Gm, G. mellonella.