TABLE 3 .
Outcome and signature taxonomical group | Relative abundance (%) at: |
|||||
---|---|---|---|---|---|---|
Pre | Day 1 | Day 2 | Day 5 | End | TOC | |
Organisms in resolvers | ||||||
Propionibacterium spp. | 39.99b | 42.3 | 39.2b | |||
P. acnes | 38.97b* | 42.02 | 38.3 | |||
Actinobacteria | 58.3b | |||||
Organisms in pustule formers | ||||||
Proteobacteria | 37.4 | 14.4 | 18.2 | 16.4 | ||
Kocuria | 1.9c | |||||
Micrococcus spp. | 6.4b | 2.1c | 4.7 | 4.3c | 7.4b | |
M. luteus | 5.9 | 4.3 | ||||
Flavobacterium | 1.1c | 0.5 | ||||
Bacteroidetes | 6.5 | 2.6 | ||||
Corynebacterium spp. | 17.6 | 12.7 | 11.2 | |||
C. tuberculostearicum | 4.00 | 5.9c | 4.95 | 5.9 | ||
C. aurimucosum/C. accolens | 8.7 | 6.03 | 2.6 | |||
Haemophilus | 10.2b | |||||
Paracoccus | 3.3* | 12.4 | ||||
Staphylococcus spp. | 41.4 | |||||
S. capitis/S. caprae | 30.8b | 24.6 | ||||
Firmicutes | 46.0b | 40.4b | ||||
Unclassified | 1.0 |
A taxonomical group was considered “signature” if it was detected in ≥25% of sites, comprised ≥1% (at the phylum or genus level) or 0.1% (at the OTU level) of the total microbiome of resolvers or pustule formers, and its relative abundance was significantly different (P < 0.05) between resolvers and pustule formers. Pre, preinfection; End, endpoint. *, trended towards significance.
The NB model fit the data better.
The ZINB model fit the data better.