. 2015 Oct 10;7(14):1129–1134. doi: 10.4253/wjge.v7.i14.1129

Table 2.

Reported outcomes for Large Volume Single Centers after peroral endoscopic myotomy

Ref.	Study size	Myotomy thicknes/length	Morbidity	Follow up (mo)	Clinical outcome - before/after	Manometry before/after	Postop PPI
Inoue et al[14] 2013	300	Partial	Pneumothorax 0.3%	12	Eckardt - 6.13/1.33	27.3/13.4	4.9%
Inoue et al[14] 2013	300	14.1 cm	Mucosal Injury - 2.0%	12	98.2% success	27.3/13.4	4.9%
Ren et al[10] 2012	119	Partial	Pneumothorax - 25.2%	3	98.3% success	NA	NA
Ren et al[10] 2012	119	9.2 cm	Pneumoperitoneum - 39.5% Bleeding 0.8%	3	98.3% success	NA	NA
Friedel et al[15] 2013	45	Full	Mucosal Injury - 20%	3	Eckardt - 7.8/0.4	NA	NA
Friedel et al[15] 2013	45	9 cm	Pneumoperitoneum - 13%	3	95% success	NA	NA
Bhayani et al[9] 2014	37	Partial	Perforation - 10.8% Bleeding - 2.7%	6.8	Eckardt - 5.4/1.2	41/16	NA
Bhayani et al[9] 2014	37	Partial	Perforation - 10.8% Bleeding - 2.7%	6.8	Dysphagia - 0%	41/16	NA
Vigneswaran et al[17] 2014	37	Partial	Perforation - 5.4%	11.3	Eckardt - 6.8/0.6	29.1/NA	22%
Vigneswaran et al[17] 2014	37	12.8 cm	Mucosal Injury - 2.7%	11.3	100% success	29.1/NA	22%
Hungness et al[12] 2013	18	Partial	Perforation - 5.6%	6	Eckardt - 7/1	19/9	NA
Hungness et al[12] 2013	18	9 cm	Perforation - 5.6%	6	89% success	19/9	NA
von Renteln et al[7] 2012	16	Partial and full	Perforation - 0%	3	Eckardt - 8.8/1.4	27.2/11.8	6.3%
von Renteln et al[7] 2012	16	12 cm	Pneumoperitoneum - 50%	3	94% success	27.2/11.8	6.3%

NA: Not available; PPI: Proton pump inhibitor.