Fig. 3.

Unsupervised analysis of Burkitt lymphomas. a The heat map diagram shows the result of the two-way unsupervised HC of miRNAs and samples based on the expression of 1,375 miRNAs. HC, roughly discriminated MYC translocation-negative (yellow) and MYC translocation-positive (blue) cases based on the miRNA expression pattern. In the matrix, each row represents a miRNA and each column represents a sample. The color scale illustrates the relative expression level of a miRNA across all samples: red represents an expression level above the mean and green represents expression lower than the mean. b PCA confirmed the distinction between MYC translocation-positive (blue) and MYC translocation-negative (yellow) samples