Table 1.

Decay time constants of L/M (τ_L/M) and O (τ_O) intermediates of WT KR2 and its mutants

Protein	τL/M [ms]	τL/M/τL/M,WT[a]	τO [ms]	τO/τO,WT[a]
WT KR2	1.0±0.1[c]	–	8.7±0.6[b, c]	–
KR2 N112A	1200±400	1200±400[b]	nd	–
KR2 D116N	nd	–	nd	–
KR2 Q123A	5.6±0.4	5.6±0.7[d]	22.4±1.7	2.6±0.3[d]
KR2 Q123V	16.3±1.5	16.3±2.2	157±6	18.2±1.5

[a] τ_L/M/τ_L/M,WT and τ_O/τ_O,WT represent the ratio of τ_L/M and τ_O of mutants compared to WT KR2, respectively. [b] This decay process is biexponential and the value of the weighted average of the components (see the Supporting Information) is shown. [c] Ref. [4]. [d] Ref. [5]. nd=not detected.