Fig. 2.

Analysis of the proteins and markers of fibrinolysis in symptom-free periods and during attacks in the same C1-INH-HAE patients (Panels a-d). Each patient is represented by a single value that was calculated as the mean in case several attacks had occurred. The results of the patients and of the healthy controls were compared using the Mann–Whitney test; whereas the “symptom-free” or “during attack” results of the same patients were compared with the paired t-test. PAI-1 levels were available only from 12 healthy subjects