Table 5.
Predictors of day-28 mortality in univariate and stepwise multivariate Cox regression analysis
Univariable | Stepwise multivariable | |||
---|---|---|---|---|
hazard ratio (95 % CI) | p | hazard ratio (95 % CI) | p | |
SOFA score at t0MCS | 1.16 (0.95–1.4) | .14 | - | - |
Cardiac arrest before MCS | 2.35 (0.79–7.03) | .13 | - | - |
RBC transfusion by day on MCS | 1.91 (1.17–3.12) | .01 | - | - |
RRT during ICU stay | 2.13 (0.74–6.14) | .16 | - | - |
SAPS II score at ICU admission | 1.04 (1.01–1.07) | .01 | 1.04 (1.01–1.07) | 0.008 |
Vasoactive-inotropic score before Impella | 1.00 (0.998–1.01) | .18 | 1.01 (1.00–1.02) | .035 |
Post-AMI cardiogenic shock | 3.06 (1.02–9.16) | .05 | 4.14 (1.20–14.25) | .024 |
Cardiogenic shock from dilated cardiomyopathy | 0.57 (0.16–2.06) | .40 | Not included | |
Postcardiotomy cardiogenic shock | 0.32 (0.04–2.44) | .27 | Not included | |
Cardiogenic shock from other etiologies | 0.61 (0.08–4.63) | .63 | Not included |
All patient variables related to mortality in univariate analysis, defined by p < 0.2 and cardiogenic shock etiologies subgroups are reported. Variables with p ≥ 0.2 were not included in the model. The first four variables entered into the model were not independently associated with mortality in the stepwise multivariable model
SOFA Sepsis-Related Organ Failure Assessment, t0MCS time of first initiation of MCS, MCS mechanical circulatory support, RBC red blood cells, RRT renal replacement therapy, ICU intensive care unit, SAPS II Simplified Acute Physiology Score II, AMI acute myocardial infarction