Table 3.
Potential targets of miR-19b
| Expression change after miR-19b knockdown | Functions | Reference | |
|---|---|---|---|
| NDRG1 | Down regulated | Metastatic suppressor | [38] |
| EPCAM | Up regulated | Cancer cell stemness | [38–41] |
| HIF1A | Up regulated | Angiogenesis; Proliferation | [43, 44] |
| HMGB2 | Up regulated | Proliferation; Predict survival of HCC | [45] |
| MAPK14 | Up regulated | Drug resistance | [42] |
NDRG1 N-myc downstream regulated gene 1, EPCAM epithelial cell adhesion molecule, HIF1A hypoxia inducible factor 1, alpha subunit, HMGB2 high mobility group box 2, MAPK14 mitogen-activated protein kinase 14