Table 1.

Cases of culture confirmed B. pseudomallei infection in CF

Patient	Year isolated	Location of acquisition	Country of residence	Age	Gender	CFTR Mutation	FEV1%	BMI	Co-pathogens	ETOH >40 g daily	Diabetes
1 (O’Carroll, 2003) [12]	1987	Northern Australia	Australia	21	M	F508del/F508del	49	21	Pseud	No	No
2	Early 1990’s	Northern Australia	Australia	40	M	F508del/R117	44.5	23	Pseud	Yes	No
									Mycobacterium intracellulare
3 (Schülin, 2001) [14]	1992	Likely Thailand	Germany	31	M	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown
4 (Visca, 2001) [15]	1998	South-East Asia	Italy	25	F	Unknown	Unknown	Unknown	Pseud	Unknown	Unknown
									BCp
5 (Dance, 1999) [11]	1998	Malaysia	England	20	M	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown
6 (Holland, 2002) [16]	1999	Northern Australia	New Zealand	8.5	M	G551D/1717-16 > A	46	15	Pseud	No	No
									Aspergillus fumigatus
7 (Holland, 2002) [16]	2000	Northern Australia	New Zealand	7	F	G551D/1717-16 > A	Unknown	19	Haemophilus influenzae	No	No
									Staph A
8 (O’Carroll, 2003) [12]	2000	Northern Australia	Australia	21	M	F508del/F508del	35	22	Pseud	No	Yes
									Staph A
									BCp
9a (Holland, 2002) [16]	2000	Northern Australia	Australia	18	M	F508del/F508del	45	21	Pseud	Yes	No
									Staph A
									BGl
									Mycobacterium intracellulare
									Other
10 (O’Carroll, 2003) [12]	2001	Northern Australia	Australia	14	M	F508del/G542X	80	17	Pseud	No	No
									Staph
11 (Holland, 2002) [16]	2001	Northern Australia	New Zealand	38	M	F508del/F508del	36	19	Pseud	No	IFG
									Staph A
12 (O’Carroll, 2003) [12]	2001	Northern Australia	Australia	25	F	Unknown	80	20	Pseud	No	No
									Staph A
									BCp
13 (Asiah, 2006) [8]	2004	Malaysia	Malaysia	17	M	Unknown	Unknown	Unknown	Pseud	Unknown	Unknown
									Staph A
14 (Barth, 2007) [9]	2005	Brazil	Brazil	17	F	Unknown	Unknown	Unknown	Pseud	Unknown	Unknown
									Staph A
15	2005	Thailand	England	30	F	Unknown	56	21	Pseud	No	Yes
									Staph A
									Aspergillus fumigatus
16 (Corral, 2008) [10]	2006	British Virgin Islands	England	17	M	F508del/E60X	63	22	Pseud	Unknown	No
									Staph A
			Canada
17	2007	Northern Australia	Australia	38	M	F508del/F711 + 5G > A	29	19	Pseud	No	No
									Staph A
									Aspergillus terreus
18	2007	Thailand	New Zealand	10	F	F508del/17aa + IG74	107	16	Pseud	No	No
									Staph A
									Other
19	2008	Thailand	Australia	22	F	F508del/F508del	85	23	Pseud	Yes	Yes
20 (O’Sullivan, 2011) [13]	2009	Aruba	USA	7	F	F508del/F508del	88	13	None	No	No
21	2010	Vietnam/Cambodia	England	23	F	F508del/F508del	44	19	Pseud	No	No
									Haemophilus influenzae
22 (Radhakrishna, 2014) [17]	2011	Thailand	Australia	25	M	Unknown	95	24	Pseud	Unknown	No
									Aspergillus fumigatus
23	2012	Malaysia/Philippines	Malaysia	19	M	R553X/unknown	18	17	Pseud	No	No
24	2013	Thailand/Japan	England	30	M	F508del/E60X	67	23	Pseud	No	No
25	2015	Thailand	England	21	F	F508del/F508del	71	18	Pseud	No	No
									Staph A

Pseud Pseudomona aeruginosa, Staph A Staphylococcus aureus, BCp Burkholderia cepacia complex, BGl Burkholderia gladioli, IFG impaired fasting glucos

^a3 distinct B. pseudomallei infections were recorded in this patient over 8 years