Table 2.
Three day subpressor AngII infusion (200 ng/kg/min, 3 days) does not significantly alter physiological parameters
| Physiological parameters | Control (n = 7) | AngII (n = 7) |
|---|---|---|
| Hematocrit | 0.45 ± 0.01 | 0.45 ± 0.01 |
| Plasma Na+, mmol/L | 135.6 ± 2.1 | 138.4 ± 1.0 |
| Plasma K+, mmol/L | 4.5 ± 0.1 | 4.7 ± 0.1 |
| Body wt gain per day, g | 4.8 ± 0.5 | 4.8 ± 0.5 |
| Heart wt/100 g body wt | 0.29 ± 0.01 | 0.31 ± 0.005 |
| Kidney wt/100 g body wt | 0.44 ± 0.01 | 0.43 ± 0.01 |
| Baseline overnight UV, mL | 12.3 ± 0.9 | 11.3 ± 1.0 |
| Baseline overnight UNaV, mmol | 1.9 ± 0.1 | 1.8 ± 0.1 |
| Baseline overnight UKV, mmol | 3.2 ± 0.1 | 3.1 ± 0.1 |
| Final overnight UV, mL | 13.3 ± 1.0 | 14.1 ± 1.3 |
| Final overnight UNaV, mmol | 2.1 ± 0.1 | 2.1 ± 0.1 |
| Final overnight UKV, mmol | 3.5 ± 0.1 | 3.3 ± 0.1 |
“Baseline” urine was collected 16 h overnight before minipump implantation at day 1.
“Final” urine was collected overnight before euthanizing at day 3.
UV, urine volume; UNaV, urinary Na+ excretion; UKV, urinary K+ excretion.