Table 2.
Control | Reduced | Restricted | |
---|---|---|---|
Males | |||
Food intake (g/24 h/kg) | 42 ± 1 | 39 ± 1 | 46 ± 2† |
Water intake (mL/24 h/kg) | 72 ± 4 | 66 ± 4 | 79 ± 2† |
Urine production (L/24 h/kg) | 0.036 ± 0.002 | 0.031 ± 0.002 | 0.039 ± 0.004 |
Glucose (mmol/L/24 h/kg) | 0.043 ± 0.005 | 0.044 ± 0.006 | 0.029 ± 0.008 |
Creatinine (mmol/L/24 h/kg) | 0.090 ± 0.013 | 0.099 ± 0.011 | 0.104 ± 0.021 |
Total protein (mg/L/24 h/kg) | 16.924 ± 3.105 | 20.547 ± 2.596 | 23.148 ± 5.152 |
Albumin (mg/L/24 h/kg) | 0.879 ± 0.175 | 1.031 ± 0.177 | 0.831 ± 0.199 |
Sodium (mmol/L/(24 h)/kg) | 0.648 ± 0.051 | 0.844 ± 0.081 | 0.693 ± 0.081 |
Potassium (mmol/L/(24 h)/kg) | 1.766 ± 0.152 | 1.784 ± 0.140 | 1.568 ± 0.185 |
Chloride (mmol/L/(24 h)/kg) | 2.118 ± 0.137 | 2.220 ± 0.161 | 2.050 ± 0.185 |
Females | |||
Food intake (g/24 h/kg) | 64 ± 2 | 65 ± 3 | 65 ± 4 |
Water intake (mL/24 h/kg) | 141 ± 7 | 134 ± 6 | 159 ± 11 |
Urine production (L/24 h/kg) | 0.064 ± 0.005 | 0.075 ± 0.004 | 0.091 ± 0.009* |
Glucose (mmol/L/24 h/kg) | 0.023 ± 0.003 | 0.032 ± 0.006 | 0.012 ± 0.003† |
Creatinine (mmol/L/24 h/kg) | 0.081 ± 0.012 | 0.125 ± 0.016* | 0.066 ± 0.012† |
Total protein (mg/L/24 h/kg) | 6.570 ± 0.857 | 8.906 ± 2.024 | 6.029 ± 1.096 |
Albumin (mg/L/24 h/kg) | 0.443 ± 0.090 | 0.448 ± 0.051 | 0.621 ± 0.090 |
Sodium (mmol/L/(24 h)/kg) | 1.389 ± 0.179 | 1.891 ± 0.119 | 1.508 ± 0.314 |
Potassium (mmol/L/(24 h)/kg) | 2.975 ± 0.307 | 4.296 ± 0.356* | 2.982 ± 0.345† |
Chloride (mmol/L/(24 h)/kg) | 3.743 ± 0.312 | 5.352 ± 0.381* | 4.239 ± 0.500 |
Food and water intake and urinary glucose, creatinine, total protein, albumin, and electrolytes (sodium, potassium, and chloride) were measured over 24 h in male and female Control, Reduced, and Restricted offspring. Values are expressed as means ± SEM; n = 10 per group).
P < 0.05 versus Control, †P < 0.05 versus Reduced.