Table 2. Factors associated with the presence of a drug resistance mutation among HIV+ participants — multivariable logistic regression model results (N=337).
| Factor | OR | p-value | AOR (95% C.I.) | p-value |
|---|---|---|---|---|
| Site | 0.190a | |||
| Isipingo vs. Botha's Hill | 1.00 | NSb | 0.67 (0.02, 26.1) | 0.831 |
| Overport vs. Botha's Hill | 1.06 | NSb | 3.79 (0.27, 53.45) | 0.323 |
| R.K. Khan vs. Botha's Hill | 1.31 | NSb | 9.29 (0.56, 154.61) | 0.120 |
| Tongaat vs. Botha's Hill | 0.87 | NSb | 7.60 (0.46, 125.78) | 0.157 |
| Umkomaas vs. Botha's Hill | 0.21 | 0.16 | 1.30 (0.05, 35.52) | 0.876 |
| Verulam vs. Botha's Hill | 0.85 | NSb | 1.13 (0.06, 19.89) | 0.936 |
| Participant age, years | 1.14 | <0.01 | 1.07 (0.98, 1.17) | 0.160 |
| Participant Some Secondary School Education or Higher | 0.32 | <0.01 | 0.40 (0.10, 1.62) | 0.197 |
| Participant has a primary sex partner | 0.19 | 0.05 | 0.03 (0.002, 0.59) | 0.020 |
| High perceived risk of getting HIV | 3.26 | <0.01 | 3.47 (1.15, 10.47) | 0.028 |
| Participant knows someone who has HIV | 0.191 a | |||
| Yes | 2.75 | 0.18 | 2.63 (0.52, 13.24) | 0.240 |
| Don't know | 1.29 | NSb | 0.75 (0.10, 5.60) | 0.780 |
| No | Ref | -- | Ref | -- |
| Participant last tested negative for HIV within past year | 0.39 | 0.14 | 0.16 (0.03, 0.89) | 0.036 |
| Participant ever participated in a microbicide trial | 4.76 | 0.01 | 5.36 (1.17, 24.51) | 0.030 |
| Participant ever taken other drugs | 0.18 | 0.10 | 0.20 (0.03, 1.64) | 0.134 |
| Husband/partner has ever been tested for HIV | ||||
| Yes | 1.82 | 0.17 | 2.35 (0.72, 7.67) | 0.158 |
| No, Don't Know or No partner | Ref | -- | Ref | -- |
| Husband/partner has been prescribed ARVs | 0.235 a | |||
| Yes | 10.46 | 0.01 | 7.04 (0.59, 83.58) | 0.122 |
| Don't know | 1.43 | NSb | 1.65 (0.58, 4.73) | 0.353 |
| No | Ref | -- | Ref | -- |
| Friend/family member has been prescribed ARVs | 0.810 a | |||
| Yes | 3.31 | 0.06 | 1.62 (0.38, 7.02) | 0.517 |
| Don't know | 2.35 | NSb | 1.47 (0.32, 6.83) | 0.624 |
| No | Ref | -- | Ref | -- |
a
For nominal variables with more than 2 categories, e.g. site, the overall p-value comes from the Type 3 analysis Wald Chi-Square test, which assesses whether all categories of that variable are the same. For each category, p-values are also provided from an analysis of maximum likelihood estimates Wald Chi-Square tests for a comparison to a reference, as indicated.
b
NS = Non-significant p-value >0.20.