Table E1.
Characteristics of children with 0, 1, or 2 or more exacerbations
| No. of exacerbations |
P value |
||||
|---|---|---|---|---|---|
| 0 | 1 | ≥2 | 0 vs ≥2 | 1 vs ≥2 | |
| No. of children | 40 | 23 | 39 | ||
| Sex | 17 F, 23 M | 7 F, 16 M | 15 F, 24 M | .71 | .52 |
| Maternal asthma | 50% | 39% | 51% | .91 | .35 |
| Paternal asthma | 33% | 36% | 33% | 1.00 | .81 |
| Maternal allergy | 90% | 83% | 84% | .44 | .87 |
| Paternal allergy | 84% | 75% | 86% | .78 | .30 |
| Aeroallergen sensitization (sIgE), year 6 (kU/L) | 60% | 41% | 63% | .81 | .14 |
| Aeroallergen sensitization (sIgE), year 11 (kU/L) | 74% | 44% | 78% | .73 | .02 |
| Total IgE, year 6 (kU/L) | 51 (25-126) | 46 (9-129) | 96 (25-280) | .62 | .09 |
| Total IgE, year 11 (kU/L) | 49 (26-460) | 59 (18-228) | 119 (44-472) | .53 | .04 |
| Positive skin test response, year 9 | 56% | 47% | 62% | .60 | .29 |
| Feno, year 6 (ppb) | 9.1 (7.2-11.1) | 5.9 (4.7-11.0) | 7.9 (6.1-18.3) | .74 | .14 |
| Feno, year 8 (ppb) | 8.1 (7.0-10.1) | 8.9 (5.2-20.0) | 10.6 (7.6-28.7) | .14 | .28 |
| Feno, year 11 (ppb) | 15.0 (9.4-24.5) | 10.6 (8.8-24.6) | 15.7 (8.7-32.4) | .76 | .61 |
| Blood eosinophils (%), year 6 | 3.0 (1.0-5.0) | 2.5 (1.0-4.0) | 3.0 (1.0-5.2) | .71 | .96 |
| Blood eosinophils (%), year 8 | 4.0 (2.0-5.0) | 2.5 (1.0-5.0) | 4.0 (2.5-5.5) | .45 | .04 |
| Blood eosinophils (%), year 11 | 5.0 (2.0-6.0) | 4.0 (1.0-5.2) | 4.0 (2.0-6.0) | .69 | .18 |
F, Female; Feno, fraction of exhaled nitric oxide; M, male; ppb, parts per billion.