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. Author manuscript; available in PMC: 2016 Oct 15.
Published in final edited form as: Biochem Pharmacol. 2015 Jul 29;97(4):566–575. doi: 10.1016/j.bcp.2015.07.030

Fig. 13.

Fig. 13

Baseline PET/[18F]ASEM TAC’s (%SUV ± SD (n = 5)) in healthy human males. Abbreviations: Pu = putamen; Pr = precuneous; Pa = parietal lobe; Th = thalamus; Fr = frontal lobe; Cg = cingulate; Oc = occipital; Tp = temporal lobe; Hp = hippocampus; CN = caudate nucleus; Cb = cerebellum; CC = corpus callosum. The distribution of [18F]ASEM in the human brain regions is comparable with non-human primate (see for review [34]) and human post-mortem distribution of α7-nAChR [47-48]. The brain kinetics of [18F]ASEM are reversible. Reprinted from[68] with permission of Copyright Clearance Center's RightsLink service.