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. Author manuscript; available in PMC: 2016 Oct 15.
Published in final edited form as: Biochem Pharmacol. 2015 Jul 29;97(4):566–575. doi: 10.1016/j.bcp.2015.07.030

Fig. 6.

Fig. 6

Regional distribution of [18F]ASEM in CD-1 mice. Data: mean %injected dose/g tissue ± SD (n = 3). Abbreviations: Coll = superior and inferior colliculus; Hipp = hippocampus; FrCtx = frontal cortex; Rest = rest of brain; Str = striatum; CB = cerebellum. Reprinted from [48] with permission of Copyright Clearance Center's RightsLink service. The study demonstrated that [18F]ASEM exhibits high brain uptake with regional distribution that matches the distribution of the α7-nAChR in the rodent brain and reversible brain kinetics.