Table 1.
Demographic, biochemical and ultrasonographic characteristics of the two patients at the time of the diagnosis of pancreatic adenocarcinoma
| Case n° 1 | Case n° 2 | |
|---|---|---|
| Age, year | 63 | 66 |
| Gender | Male | Male |
| Time of observation | 2010 | 2007 |
| Months between diagnosis of pancreatic adenocarcinoma and GIST | 0 | 39 |
| Red Blood cells, cells/ml | 4.45E6 | 4.30E6 |
| Haemoglobin, g/dl | 14.7 | 14.3 |
| White Blood Cells, cells/ml | 4.6E3 | 4.2E3 |
| Platelet count, cells/ml | 242E3 | 69E3 |
| AST, IU/ml | 111 (n.v. 10-40) | 35 (n.v. <45) |
| ALT, IU/ml | 183 (n.v. 10-60) | 49 (n.v. <63) |
| Total bilirubin, mg/dl | 11,2 mg/dl (n.v <1.2) | 1.13 mg/dl (n.v <1) |
| Direct bilirubin, mg/dl | 5.8 mg/dl (n.v. <0,4) | 0.55 mg/dl (n.v. <0,2) |
| ALP, IU/ml | 197 (n.v. 38-126) | 89 (n.v. 30-122) |
| γ-GT, IU/ml | 406 (n.v. <50) | 31 (n.v. <50) |
| INR (normal value) | 1 (0.8-1.3) | 1.18 (0.8-1.2) |
| Ca19-9, IU/ml | 647 (n.v. <33) | 287.3 (n.v. <37) |
| HCV Ab | Negative | Positive |
| Pancreas Ultrasound characteristics |
Hypoechoic mass of 31 × 39 mm in the head of pancreas | A hypoechoic, irregular-shaped mass of 4 cm in the body of the Pancreas |
| CEUS characteristics | Arterial phase and enhancement with fine spot composing a wire aspect, persisting homogeneously hypoechoic in the late phases | A rapid enhancement in arterial phase with a persisting homogeneously hypoechogenecity in the late phases |
Footnotes: AST: aspartate transaminase; n.v.: normal value; ALT: alanine transaminase; ALP: Alkaline phosphatase; CA 19-9: Carbohydrate Antigen 19.9; CEUS: Contrast Enhanced Ultrasound; γ-GT: gamma glutamyl transferases; GIST: gastrointestinal stromal tumor; HCV Ab: hepatitis C virus antibodies; INR: International Normalized Ratio