Table 1.
Group | Sham + Veh | Sham + LiCl | P value∗ | MCAO + Veh | MCAO + LiCl | P value∗ |
---|---|---|---|---|---|---|
n | 9 | 9 | NS | 29 | 28 | NS |
Weight (g); mean ± SEM | 363.4 ± 5.6 | 362.3 ± 4.7 | NS | 376.2 ± 3.9 | 378.3 ± 3.5 | 0.693 |
Rats with visible NDs at 24 h; number (%) | 0 (0) | 0 (0) | NS | 21 (100) | 21 (100) | NS |
Mortality after 24 h; number (%) | 0 (0) | 0 (0) | NS | 8 (27.6) | 7 (25) | 0.532 |
At 2 h before surgery vehicle-treated rats were injected (ip) with 0.35 mL NaCl 0.9% and LiCl-treated rats with 100 mg/kg lithium. Existence of NDs was assessed in surviving rats at 24 h after surgery as described in Section 2. Mortality was followed during 24 h after surgery. This table represents the results of the two experiments conducted in this study. ∗Comparisons for statistical significance were done only between groups that underwent the same surgical procedure, that is, Sham + Veh versus Sham + LiCl; MCAO + Veh versus MCAO + LiCl. LiCl, lithium chloride; MCAO, middle cerebral artery occlusion; ND, neurological deficit; NS, nonsignificant; Veh, vehicle.