Table 1.
Comparison of the clinicopathological features between patients with and without hepatoduodenal lymph node metastasis n (%)
| n |
HDLN metastasis |
Univariate |
Multivariate |
|||
| Positive | Negative | P value | OR (95%CI) | P value | ||
| Total | 276 | 26 | 250 | |||
| Sex | ||||||
| Male | 186 | 16 (62) | 170 (68) | |||
| Female | 90 | 10 (38) | 80 (32) | 0.509 | - | |
| Age (yr) | ||||||
| < 65 | 134 | 10 (38) | 124 (50) | |||
| ≥ 65 | 142 | 16 (62) | 126 (50) | 0.277 | - | |
| Tumor location | ||||||
| U | 64 | 2 (8) | 62 (25) | |||
| M and L | 212 | 24 (92) | 188 (75) | 0.029 | 5.88 (1.61-38.1) | 0.005 |
| CA 19-9 (U/mL) | ||||||
| < 10 | 132 | 9 (35) | 123 (49) | |||
| ≥ 10 | 144 | 17 (65) | 127 (51) | 0.153 | - | |
| CEA (ng/mL) | ||||||
| < 3 | 195 | 16 (62) | 179 (72) | |||
| ≥ 3 | 81 | 10 (38) | 71 (28) | 0.295 | - | |
| Histopathological type | ||||||
| Differentiated | 135 | 10 (38) | 125 (50) | |||
| Undifferentiated | 141 | 16 (62) | 125 (50) | 0.260 | - | |
| Venous invasion | ||||||
| (-) | 173 | 12 (46) | 161 (64) | |||
| (+) | 103 | 14 (54) | 89 (36) | 0.072 | - | |
| Lymphatic invasion | ||||||
| (-) | 105 | 3 (12) | 102 (42) | |||
| (+) | 171 | 23 (88) | 148 (58) | 0.002 | - | |
| Tumor size (mm) | ||||||
| < 45 | 119 | 5 (19) | 114 (46) | |||
| ≥ 45 | 157 | 21 (81) | 136 (54) | 0.007 | - | |
| T category | ||||||
| T1 and T2 | 127 | 3 (12) | 124 (50) | |||
| T3 and T4 | 149 | 23 (88) | 126 (50) | < 0.0001 | 4.45 (1.28-21.3) | 0.017 |
HDLN: Hepatoduodenal lymph node; CEA: Carcinoembryonic antigen; CA 19-9: Carbohydrate antigen 19-9; U: Upper gastric body; M: Middle gastric body; L: Lower gastric body.