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. Author manuscript; available in PMC: 2016 Oct 13.
Published in final edited form as: Vaccine. 2015 Jul 17;33(42):5715–5722. doi: 10.1016/j.vaccine.2015.07.010

Fig. 4. Lack of correlation between cellular responses to SIV Gag after vaccination and baseline Mtb antibody responses.

Fig. 4

Rhesus macaques (n=20) were immunized with rBCG expressing SIV Gag, then boosted 10 months later with recombinant NYVAC expressing SIV Gag and SIV Pol. Cellular responses to SIV Gag were measured two weeks after the initial rBCG prime and two weeks after the rNYVAC boost. Each panel shows cellular responses to SIV Gag on the y-axis, and baseline Mtb humoral responses on the x-axis. Shown are peak IFN-γ ELISpot responses to an SIV Gag peptide pool after prime (A) and boost (B), and tetramer binding to the SIV Gag p11C epitope after prime (C) and boost (D). No significant correlation was seen between cellular responses to SIV Gag and baseline Mtb antibody responses.