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. Author manuscript; available in PMC: 2016 Sep 7.
Published in final edited form as: Cytoskeleton (Hoboken). 2015 Sep 7;72(8):422–433. doi: 10.1002/cm.21237

Fig. 9.

Fig. 9

zIQGAP3 acts downstream to FGFR1 and Ras. (A) Phenotypes of zIQGAP3 morphants and of embryos overexpressing DN-FGFR1 and DN-Ras compared to a WT embryo at the same developmental stage. A WT embryo is shown on the top (yellow), weak phenotypes on bottom left (light blue) and strong phenotypes on bottom right (dark blue). (B) Percentage of the different phenotypes observed in the population of embryos injected with DN-FGFR1 mRNA (500 pg; n = 101) or DN-Ras mRNA (200 pg; n = 144) alone, or in combination with 1 ng of zIQGAP3 mRNA. The phenotypic rescue by coinjection of zIQGAP3 mRNA with either DN-FGFR1 (n = 112) or DN-Ras (n = 112) indicates that zIQGAP3 acts downstream of FGFR1 and Ras.