Figure 5. admp1 is expressed in the ventral organizer while admp2 is expressed in the dorsal-vegetal ectoderm.

(a) admp1 expression starts at mesenchyme blastula, first in a few ventral ectodermal cells near the animal pole, then it spreads vegetally to occupy a territory on the midline of the ventral ectoderm. At prism stage, novel territories expressing admp1 appear in the animal pole region and in the ventral-most endoderm. In embryos with duplicated D/V axes, admp1 is expressed at the centre of each oral lobe. (b) admp2 expression is initiated at the late blastula stage in the dorsal-vegetal plate. During gastrulation admp2 expression persists in a thin layer of dorsal-vegetal ectodermal cells and at prism stage in cells that will give rise to the dorsal apex of the pluteus larva. In embryos with duplicated D/V axes, admp2 is expressed in two opposing territories corresponding to the duplicated dorsal-vegetal ectoderm. Scale bar, 10 μm.