Table 2.
The levels of circulating IgG antibodies to BIRC5 and MYC in NSCLC.
| Sample | Patient (n) | Control (n) | t1 | P2 |
|---|---|---|---|---|
| Discovery | ||||
| BIRC5 | 0.87 ± 0.14 (49) | 0.90 ± 0.42 (108) | –0.43 | 0.665 |
| MYC | 0.86 ± 0.30 (49) | 0.72 ± 0.14 (108) | 3.96 | 0.0001 |
| Validation | ||||
| BIRC5 | 0.78 ± 0.19 (60) | 0.77 ± 0.37 (108) | 0.13 | 0.894 |
| MYC | 0.90 ± 0.27 (60) | 0.86 ± 0.16 (108) | 1.24 | 0.217 |
The antibody levels are expressed as mean ± SD in SBI.
1
Student’s t-test (two-tailed).
2
Combining probabilities: X2 = 1.04, df = 4, P = 0.904 for anti- BIRC5 IgG levels and X2 = 21.19, df = 4, P = 0.0003 for anti-MYC IgG levels.