Table 2.
Morphometric features and nuisance predictors related to head motion and quality of spatial normalization.
| Controls | bvFTD | T statistics | p-Value | Effect-size (r) | Cohen's d | |
|---|---|---|---|---|---|---|
| GM (ml) | 426.52 (56.82) | 363.22 (56.89) | 3.259 | 0.002288* | −0.4494 | −1.1137 |
| WM (ml) | 726.10 (86.22) | 718.59 (88.63) | 0.253 | 0.801589 | −0.039 | −0.0864 |
| CSF (ml) | 219.24 (30.48) | 286.21 (57.99) | −4.904 | 0.000016* | 0.6034 | 1.6751 |
| TIV (ml) | 1371.86 (135.34) | 1368.03 (110.07) | 0.087 | 0.931028 | −0.0134 | −0.0297 |
| GM/TIV percentage (%) | 31.06 (2.45) | 26.54 (3.46) | 4.77 | 0.000024* | −0.5941 | −1.6349 |
| Average scan-to-scan head motion (mm) | 0.063 (0.03) | 0.079 (0.03) | −1.47 | 0.147 | 0.2342 | 0.5333 |
| Quality of normalization (smoothed) | 0.963 (0.005) | 0.961 (0.006) | 0.880553 | 0.383820 | −0.1682 | −0.3778 |
| Quality of normalization (unsmoothed) | 0.923 (0.007) | 0.920744 (0.009) | 1.061066 | 0.295025 | −0.1329 | −0.2967 |
For each variable, the mean (and standard-deviation in brackets), T statistics and p-value of group comparisons, as well as effects sizes, are reported. The asterisk in the “p-value” column denotes the statistics reported as significant.
bvFTD: behavioral variant of frontotemporal dementia; ml: milliliters; GM: gray matter; WM: white matter; CSF: cerebrospinal fluid; TIV: total intracranial volume.