Table 8.
Summary statistics (median values and 95% interval) for the physiology of a 16 year old Hispanic woman and a 49 year Caucasian women and corresponding summary statistics from the prior distributions of Allen et al. (2007).
| Parameter | Hispanic, aged 16 | Caucasian, aged 49 | Allen et al. (2007) |
|---|---|---|---|
| Body weight (kg) | 57.6 (41.9, 80.2) | 68.2 (46.9, 89.5) | 67.4 (34.0, 129.4) |
| Liver mass | 1.49 (0.70, 2.42) | 1.49 (0.67, 2.40) | 1.67 (0.46, 4.31) |
| Kidney mass | 0.32 (0.15, 0.50) | 0.32 (0.15, 0.51) | 0.26 (0.05, 0.70) |
| Brain mass | 1.29 (1.18, 1.41) | 1.21 (1.11, 1.35) | 1.26 (0.27, 3.40) |
| Intestine mass | 0.87 (0.68, 1.09) | 0.87 (0.68, 1.09) | 0.89 (0.16, 2.37) |
| Gut mass | 0.12 (0.08, 0.16) | 0.12 (0.08, 0.16) | 1.12 (0.45, 2.57) |
| Rapidly perfuseda tissue mass | 1.09 (0.61, 1.93) | 1.09 (0.61, 1.93) | 6.43 (1.23, 16.97) |
| Slowly perfusedb tissue mass | 21.45 (12.91, 32.26) | 21.0 (11.91, 32.40) | 22.69 (9.18, 53.16) |
| Adipose mass | 18.2 (6.34, 43.20) | 29.4 (10.60, 54.50) | 17.8 (4.30, 52.64) |
| Remainder (non-perfused) | 8.70 (8.15, 9.3) | 8.85 (8.31, 9.40) | 7.8 (1.60, 21.0) |
| Cardiac Output (l/min) | 5.90 (5.55, 6.25) | 5.10 (4.75, 5.45) | 7.6 (2.73, 16.3) |
| Liver flow | 0.41 (0.37, 0.45) | 0.35 (0.31, 0.39) | 0.32 (0.076, 0.96) |
| Kidney flow | 1.17 (1.08, 1.27) | 1.02 (0.92, 1.11) | 1.23 (0.22, 1.23) |
| Brain flow | 0.76 (0.69, 0.82) | 0.66 (0.59, 0.73) | 0.80 (0.15, 2.34) |
| Gut flowc | 1.06 (0.97, 1.14) | 0.91 (0.83, 0.99) | 1.28 (0.19, 3.84) |
| Rapidly perfuseda tissue flow | 0.67 (0.62, 0.72) | 0.58 (0.53, 0.64) | 1.28 (0.24, 3.89) |
| Slowly perfusedb tissue flow | 1.00 (0.91, 1.07) | 0.86 (0.79, 0.94) | 1.77 (0.31, 5.24) |
| Adipose flow | 0.53 (0.48, 0.58) | 0.46 (0.41, 0.51) | 0.38 (0.05, 1.88) |
a
Rapidly perfused compartment assumed to comprise of the heart, lung, spleen, pancreas and sexual organs.
b
Slowly perfused compartment assumed to comprise of skin and skeletal muscle.
c
Comprising of gut and intestine flows.