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Properties of the F-ATP synthase channel across species
| Conductance, pS | Matrix Ca2+ | Matrix Mg2+/ADP | Pi | CsA | Matrix CyP | |
|---|---|---|---|---|---|---|
| S. cerevisiae | 300 | Activates | Inhibits | Inhibits | No effect | Yes |
| D. melanogaster | 53 | Activates | Inhibits | Inhibits | No effect | No |
| Mammals | 500 | Activates | Inhibits | Activates | Inhibits | Yes |
The conductance of F-ATP synthase channels and the effects of some PTP effectors in the indicated organisms are summarized. CsA, cyclosporin A; CyP, cyclophilin.
