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Multiple cell fates are associated with DNA synthesis and reexpression of cell cycle proteins. Multinucleation (DNA replication with karyokinesis but no cytokinesis), polyploidization (DNA replication without karyokinesis or cytokinesis), fusion of nonmyocytes with cardiac myocytes, or DNA repair can all be associated with DNA synthesis and/or reexpression of cell cycle proteins but does not necessarily represent true cardiac myocyte division.
