Effect of compounds 1c, 2b, 3f, and 5-fluorotryptamine on MPO intermediates. Difference
spectra
resulting from the addition of 250 μM H2O2 to purified MPO (1.2 μM) in the absence or presence of 10
μM inhibitor, 1% DMSO, and 150 mM NaCl in 50 mM potassium phosphate
buffer, pH 7.4.