Table 1. Serum metabolic markers and whole blood glucose concentration in 12-month-old mice.

	GPR3 WT	GPR3 Het	GPR3 KO
glucose (mg/dL)	143.10 ± 7.83	169.82 ± 16.68	153.67 ± 13.38
insulin (ng/mL)	1.63 ± 0.21	1.78 ± 0.39	1.38 ± 0.16
C peptide (pmol/L)	655.14 ± 48.87	684.65 ± 49.88	632.71 ± 29.88
glucagon (pg/mL)	159.09 ± 32.47	119.81 ± 16.93	163.89 ± 17.45
leptin (ng/mL)	7.81 ± 1.23	12.22 ± 3.25	14.25 ± 2.31*
adiponectin (ng/mL)	21.53 ± 1.16	25.04 ± 1.60	22.60 ± 0.56
triglyceride (mg/dL)	101.67 ± 5.10	134.91 ± 21.92	112.57 ± 8.74
cholesterol (mg/dL)	127.33 ± 4.45	124.00 ± 5.05	136.00 ± 3.49
ALT (U/L)	120.00 ± 6.03	110.18 ± 4.19	122.29 ± 10.06
AST (U/L)	122.67 ± 6.50	109.81 ± 4.45	125.14 ± 9.05

Values are means ± s.e.m. from 10–23 mice. *P < 0.05, compared to GPR3 WT littermates, according to one-way ANOVA followed by Dunnett test.