Table 1. Family histories of cases/controls by rs11571833 status.
| Family History type | HAPS carriers | FCC carriers | FCC non-carriers | LP carriers | LP non-carriers |
|---|---|---|---|---|---|
| Breast/ovarian 1st degree | 8 (47%) | 22 (52%) | 895 (57%) | 8 (24%) | 437 (22%) |
| Breast 2nd degree | 7 (41%) | 17 (40%) | 733 (46.5%) | 11 (33%) | 552 (28%) |
| Breast/Ovarian 1st and/or Breast 2nd degree | 12 (71%) | 31 (74%) | 1210 (77%) | 14 (42%) | 832 (42%) |
| Number 1st /2nd degree with Br/Ov | NA | 1.21 | 1.45 | 0.70 | 0.58 |
| Other cancer only, 1st degree | 5 (29%) | 11 (26%) | 352 (22%) | 11 (33%) | 788 (40%) |
| Bowel cancer 1st degree | 3 (18%) | 11 (26%) | 189 (12%) | 4 (12%) | 287 (15%) |
| Other cancer only, 2nd degree1 | 3 (18%) | 19 (45%) | 502 (31.8%) | 11 (33%) | 635 (37%) |
| No. with family history recorded | 17 | 42 | 1578 | 33 | 1956 |
| No. without family history recorded | 7 | 0 | 16 | 0 | 7 |
1Denominator different for Lifepool as some 2nd degree family history not known.