Table 1.

Inclusion and exclusion criteria for the UNITE study

Descriptions
Inclusion criteria
1.	Men who played American football or ice hockey at the professional or Olympic level or who played at the collegiate, semiprofessional, or junior level for at least 2 years
2.	Men who played a high-risk contact sport, other than American football or ice hockey, at the professional or Olympic level
3.	Women who played a high-risk contact sport at the professional, Olympic, or collegiate level
4.	Men or women who played a high-risk contact sport at the professional, Olympic, collegiate, or high school level who died before the age of 35 years
5.	Men or women who played a high-risk contact sport at the professional, Olympic, collegiate, or high school level who were diagnosed with ALS during life
6.	Men or women with a military history of combat exposure
7.	Women with a history of domestic abuse
Exclusion criteria
1.	Specimen with a postmortem interval before fixation of longer than 72 h
2.	Specimen that was embalmed following brain autopsy
3.	Specimen of less than one full hemisphere

ALS, Amyotrophic lateral sclerosis; UNITE, Understanding Neurologic Injury and Traumatic Encephalopathy