Table 2.
In vitro antifungal activity of, FLC, ITZ, PSC, VRC, AMB and CFG against the 7 strains of Trichosporon using the E-test method
| Fluconazole | Itraconazole | Posaconazole | Voriconazole | Amphotericin B | Caspofungin | |
|---|---|---|---|---|---|---|
| Strain | MIC (μg/ml) | MIC (μg/ml) | MIC (μg/ml) | MIC (μg/ml) | MICa (μg/ml) | MIC (μg/ml) |
| T. asahii04 | 4.0 | 0.38 | 0.25 | 0.064 | 0.38 | >32 |
| T. asahii05 | 0.75 | 0.064 | 0.47 | 0.032 | 2.0 | >32 |
| T. asahii07 | 0.75 | 2.0 | 0.38 | 0.064 | 0.38 | >32 |
| T. asteroides01 | 1.5 | 0.047 | 0.47 | 0.032 | 0.25 | >32 |
| T. asteroides 06 | 0.75 | 1.5 | 0.25 | 0.047 | 1.0 | >32 |
| T. asteroides 13 | 0.5 | 0.5 | 0.064 | 0.023 | 0.19 | >32 |
| T. inkin | 0.38 | 1.0 | 0.19 | 0.064 | 0.064 | >32 |
a
For amphotericin B the MIC corresponded to the concentration that produced a complete inhibition of growth (100%). For the rest of the drugs, the MIC corresponded to an eminent growth inhibition (80%).