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Summary diagram of Rho GTPases and their upstream regulators and downstream effectors during clearance phagocytosis mediated by αv integrins and TAM receptors, or during anti-pathogen phagocytosis via Fc receptors, dectin-1, or αMβ2 integrin/CR3. Phagocytosis triggered by engagement of different surface receptors uses complex and overlapping cytosolic proteins upstream and downstream of Rho GTPases. For details and references please consult the main text.
