mRNA expression of coagulant factors in mice liver. The RT-PCR analysis for coagulant-factor-mRNA was measured according to gel intensities. The mRNA levels of coagulant factors FI, FII, FV, FVII, FVIII, FIX, FX, FXI, and FXIII were detected using RT-PCR and liver samples from mice treated with or without PA or LT for 72 h. Data were first normalized with internal control actin; untreated groups were subsequently adjusted to 100% during each time course. *P < 0.05, **P < 0.01, compared to respective PA-treated groups (n = 6).