Table 6.
The influence of rmpA and/or rmpA2 mutation on the virulence (LD50) of KP isolates with various microbiologic characteristics
| PCR for |
Mutation of |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Strain | Source | Capsule | ESBL | HV | rmpA | rmpA2 | rmpA | rmpA2 | LD50 |
| KP379 | blood | K2 | − | + | + | − | normal | − | 1.8 x 102 |
| KP309 | urine | K2 | − | − | + | + | mutated | mutated | 2.1 x 103 |
| KP291 | urine | K2 | − | − | + | − | mutated | − | >5 × 107 |
| KP449 | sputum | K1 | − | + | + | + | normal | mutated | 8.1 x 102 |
| KP420 | sputum | K1 | SHV-5 | − | + | + | mutated | mutated | >5 × 107 |
| KP537 | urine | K1 | SHV-5 | − | − | − | − | − | >5 × 107 |
| KP277 | urine | Non-K1/K2 | SHV-5 | − | − | − | − | − | >5 × 107 |
| KP491 | blood | Non-K1/K2 | − | − | − | − | − | − | >5 × 107 |
| KP493 | sputum | Non-K1/K2 | − | + | + | + | normal | mutated | 1.2 x 102 |
| KP290 | blood | Non-K1/K2 | SHV-5 | + | + | + | normal | mutated | 59.9 |
| KP570 | blood | K1 | SHV-12 | + | + | + | normal | mutated | 3.2 x 103 |
| KP331 | Urine | Non-K1/K2 | SHV-5 | + | − | − | − | − | >5x107 |
Note: +: positive; −: negative.