FIG. 4.

HER2 expression in cells used and cytotoxic assay. (A) Western blot of HER2 expression in HMEpC, MCF-7, and SKBR3 cells. α-tubulin as loading control. Ratios of band intensity of HER2 relative to α-tubulin are indicated below the images. (B) Cytotoxicity of ¹¹¹In-trastuzumab and ¹¹¹In-trastuzumab-NLS in HMEpC, MCF-7, and SKBR3 cells. Bars show the ratio of absorbance of alamarBlue indicator dye when the absorbance in untreated cells considers as 1. Mean ± SD. n = 3–5. *p < 0.05. ANOVA followed by the Tukey–Kramer test. HMEpC, human mammary epithelial cells.