Table 3.

Hazard ratios of incident coronary artery disease and stroke in patients with V15.81 code using unadjusted analysis and various adjusted models

Analysis	Incident CAD	Incident stoke
	HR with 95% CI*, p-value	HR with 95% CI*, p-value
Unadjusted analysis	1.26 (1.15-1.38), <0.001	1.55 (1.38-1.73), <0.001
Adjusted analysis #1	1.38 (1.25-1.52), <0.001	1.56 (1.38-1.76), <0.001
Adjusted analysis #2	1.38 (1.25-1.52), <0.001	1.54 (1.36-1.74), <0.001
Adjusted analysis #3	1.33 (1.20-1.47), <0.001	1.49 (1.32-1.69), <0.001
Adjusted analysis #4	1.26 (1.14-1.40), <0.001	1.46 (1.29-1.65), <0.001
Adjusted analysis #5	1.35 (1.17-1.57), <0.001	1.55 (1.30-1.85), <0.001

Footnotes:

^*V15.81“-” group served as a reference group for all analyzes; HR, hazard ratio; CI, confidence interval; CAD, coronary artery disease; Adjusted analysis 1, adjusted analysis for age, gender, race, mean income, marital status, area-level housing stress, low education, low employment and persistent poverty; Adjusted analysis 2, adjusted analysis 1 plus estimated glomerular filtration rate (eGFR); Adjusted analysis 3, adjusted analysis 2 plus baseline comorbidities; Adjusted analysis 4, adjusted analysis 3 plus baseline systolic and diastolic blood pressure and body mass index. Adjusted analysis 5, adjusted analysis 4 plus adherence to antihypertensive drugs.