Fig. 3.

Global distribution of the rs1150711 risk allele (T allele) in world populations. (A) Global distribution of the risk allele (T allele) of rs1150711 in world populations. The frequency of the risk allele is highly variable in world populations. For example, it is absent in San population from Africa (black arrow), nevertheless, the risk allele (T allele) is completely fixed (frequency = 1.0) in Surui population from Brazil (red arrow). (B) Allele frequency distribution of the risk allele (T allele) of rs1150711 in four continental populations from the 1000 genomes projects. The frequency of the risk allele of rs1150711 is low in African populations. However, the risk allele is prevalent in other populations, including European, Asian, and American populations.