Fig. 2.

Brain tissue volumes in neuropsychologically (NP) defined groups of individuals with psychosis. Top panel: After adjusting for intracranial volume (ICV), total white matter volume was decreased and CSF volume increased in both NP normal and NP impaired patient groups. Bottom panel: Dividing the NP impaired group into deteriorated and compromised subgroups revealed that white matter volume reduction and increased CSF was present only in the deteriorated group; compromised patients did not differ from healthy subjects on any tissue volume. †Tissue volume adjusted for ICV. Error bars = standard error of the mean.