Table 2.
Clinical Profile of Participants With Recent-Onset Psychosis (ROP, n = 69)
| Characteristic | M ± SD | Nonsmokers (n = 35) | Smokers (n = 34) | Statistics |
|---|---|---|---|---|
| Positive symptoms | ||||
| BPRS (total score) | 30.35±8.56 | 27.41±6.85 | 33.29±9.17 | t = 2.98, df = 66, P = .004 |
| BPRS-hallucinatory behavior | 2.39±1.58 | 2.17±1.38 | 2.62±1.76 | t = 1.18, df = 67, P = .25 |
| BPRS-conceptual disorganization | 1.51±0.98 | 1.40±0.91 | 1.62±1.04 | t = 0.92, df = 67, P = .36 |
| BRPS-unusual thought content | 2.72±1.61 | 2.43±1.29 | 3.03±1.85 | t = 1.57, df = 67, P = .12 |
| BPRS-depression | 1.84±1.13 | 1.54±0.82 | 2.14±1.33 | t = 2,28, df = 67, P = .03 |
| Negative symptoms | ||||
| SANS-affective flattening | 1.87±0.79 | 1.85±0.74 | 1.88±0.86 | t = 0,13, df = 65, P = .90 |
| SANS-alogia | 1.46±0.76 | 1.32±0.53 | 1.62±0.92 | t = 1,61, df = 66, P = .11 |
| SANS-avolition | 1.88±0.76 | 1.91±0.79 | 1.85±0.76 | t = 0.33, df = 65, P = .74 |
| SANS-asociality-anhedonia | 1.74±0.80 | 1.60±0.69 | 1.88±0.88 | t = 1.48, df = 67, P = .14 |
| Comorbid substance abuse disorder | 32 (46.4%) | 9 (25.7%) | 23 (67.6%) | χ2 = 12.19, df = 1, P < .001 |
| Comorbid alcohol abuse disorder | 17 (24.6%) | 8 (22.9%) | 9 (26.5%) | χ2 = 0.12, df = 1, P = .73 |
| Medication treatment | ||||
| Risperidone | 51 (73.9%) | |||
| Aripiprazole | 10 (14.5%) | |||
| Olanzapine | 2 (2.9%) | |||
| Clozapine | 2 (2.9%) | |||
| Haloperidol | 2 (2.9%) | |||
| Quetiapine | 1 (1.5%) | |||
| Quetiapine+Aripiprazole | 1 (1.5%) | |||
Note: BRPS, Brief Psychiatric Symptom Rating Scale.