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. 2015 Oct 12;10(10):e0137905. doi: 10.1371/journal.pone.0137905

Table 1. Summary of the main studies in the literature devoted to the analysis of different acquisition factors on DTI scalar measures.

Study Analyzed parameter Analyzed Measure Main finding
[12] b-value (700-1000) FA Average FA decreases with increasing b-value.
[29] b-value (500-2500) FA, MD, AD, RD Small FA variation with varying b-value (variation depends on tissue type and age). MD, AD and RD decrease with increasing b-value.
[30] b-value FA, MD, AD, RD FA error due to PVE decreases with higher b-value. MD decreases with increasing b-value. In presence of PVE, FA decreases with higher b-values, while MD, AD and RD increase.
[31] b-value FA In regions with intermediate FA, high b-value (>3000) and low SNR produce FA underestimation and eigenvector shift.
[32] b-value FA, MD Simulated data (FA = 0.9). Correct FA estimation for b-values between 500 and 1500. FA underestimation for b-values over 3000. MD decreases with increasing b-values.
[33] b-value (160-800) FA Phantoms and real data. Increasing b-values reduces standard dev. of FA.
[34] Resolution FA Smaller voxel size increases FA.
[35] Resolution, gradient directions FA Smaller voxel size increases FA. A higher number of gradient directions decreases FA.
[36] Resolution MD MD does not change with voxel size.
[13] Gradient directions FA Simulated data. A higher number of gradient directions decreases estimated FA and its standard deviation.
[14] Gradient directions, SNR FA, MD A higher number of gradient directions decreases estimated FA and its standard deviation. Importance of a well-balanced gradient directions scheme. Higher SNR reduces standard deviation in FA and MD (simulated data).
[25] Gradient directions, SNR FA, MD A higher number of gradient directions increases estimated FA while reducing MD. Lower noise increases FA.
[37] Gradient directions FA, MD, RA 20 gradient directions are enough for FA and MD estimation. 30 are needed for RA.
[10] SNR FA, MD Higher noise increases FA, while MD does not change.