Table I.
Chromosome | From (hg19) | To (hg19) | Gene name | Exon |
---|---|---|---|---|
Custom panel Heidelberg | ||||
chr1 | 27056234 | 27056365 | ARID1A | 2 |
chr1 | 27057662 | 27057775 | ARID1A | 3 |
chr1 | 27057875 | 27058001 | ARID1A | 3 |
chr1 | 27092899 | 27093023 | ARID1A | 10 |
chr1 | 27094337 | 27094460 | ARID1A | 11 |
chr1 | 27099336 | 27099464 | ARID1A | 14 |
chr1 | 27100275 | 27100411 | ARID1A | 17 |
chr1 | 27105906 | 27106030 | ARID1A | 20 |
chr1 | 27106449 | 27106570 | ARID1A | 20 |
chr1 | 27106750 | 27106883 | ARID1A | 20 |
chr1 | 115256484 | 115256587 | NRAS | 3 |
chr1 | 115258676 | 115258805 | NRAS | 2 |
chr1 | 150549826 | 150549952 | MCL-1 | 3 |
chr1 | 150551531 | 150551670 | MCL-1 | 1 |
chr2 | 178098765 | 178098890 | NFE2L2 | 2 |
chr3 | 41266029 | 41266147 | CTNNB1 | 3 |
chr3 | 41266893 | 41267010 | CTNNB1 | 5 |
chr3 | 41275089 | 41275211 | CTNNB1 | 9 |
chr3 | 178916892 | 178917000 | PIK3CA | 2 |
chr3 | 178921523 | 178921633 | PIK3CA | 5 |
chr3 | 178928050 | 178928160 | PIK3CA | 8 |
chr3 | 178936022 | 178936106 | PIK3CA | 10 |
chr3 | 178938830 | 178938960 | PIK3CA | 14 |
chr3 | 178952038 | 178952157 | PIK3CA | 21 |
chr3 | 181430178 | 181430283 | SOX2 | 1 |
chr3 | 181430516 | 181430649 | SOX2 | 1 |
chr4 | 1803550 | 1803636 | FGFR3 | 7 |
chr4 | 1808277 | 1808409 | FGFR3 | 16 |
chr4 | 55131108 | 55131222 | PDGFRA | 5 |
chr4 | 55139749 | 55139881 | PDGFRA | 10 |
chr4 | 55140692 | 55140818 | PDGFRA | 11 |
chr4 | 55141036 | 55141156 | PDGFRA | 12 |
chr4 | 55152001 | 55152128 | PDGFRA | 18 |
chr4 | 55156632 | 55156764 | PDGFRA | 22 |
chr4 | 55592107 | 55592203 | KIT | 9 |
chr4 | 55593595 | 55593684 | KIT | 11 |
chr4 | 153245407 | 153245522 | FBXW7 | 11 |
chr4 | 153247237 | 153247369 | FBXW7 | 10 |
chr4 | 153249405 | 153249530 | FBXW7 | 9 |
chr5 | 1264501 | 1264634 | TERT | 11 |
chr5 | 1293392 | 1293528 | TERT | 2 |
chr6 | 66115100 | 66115214 | EYS | 7 |
chr6 | 66204680 | 66204810 | EYS | 5 |
chr7 | 55241602 | 55241732 | EGFR | 18 |
chr7 | 55242411 | 55242544 | EGFR | 19 |
chr7 | 55248974 | 55249100 | EGFR | 20 |
chr7 | 55259416 | 55259546 | EGFR | 21 |
chr7 | 92300724 | 92300853 | CDK6 | 5 |
chr7 | 92403995 | 92404124 | CDK6 | 3 |
chr7 | 116411944 | 116412066 | MET | 14 |
chr7 | 116417426 | 116417508 | MET | 16 |
chr7 | 140453110 | 140453232 | BRAF | 15 |
chr7 | 140481387 | 140481511 | BRAF | 11 |
chr8 | 38275705 | 38275835 | FGFR1 | 10 |
chr8 | 38282107 | 38282241 | FGFR1 | 7 |
chr8 | 128751156 | 128751293 | MYC | 2 |
chr8 | 128752956 | 128753086 | MYC | 3 |
chr9 | 5069993 | 5070100 | JAK2 | 12 |
chr9 | 5073678 | 5073788 | JAK2 | 14 |
chr9 | 5126715 | 5126797 | JAK2 | 25 |
chr9 | 21970912 | 21971032 | CDKNA2 | 2 |
chr9 | 21971086 | 21971218 | CDKNA2 | 2 |
chr9 | 21974672 | 21974792 | CDKNA2 | 1 |
chr9 | 139401722 | 139401834 | NOTCH1 | 22 |
chr9 | 139404170 | 139404306 | NOTCH1 | 18 |
chr9 | 139412260 | 139412400 | NOTCH1 | 8 |
chr9 | 139413034 | 139413159 | NOTCH1 | 6 |
chr10 | 89624207 | 89624322 | PTEN | 1 |
chr10 | 89685258 | 89685374 | PTEN | 3 |
chr10 | 89692864 | 89692987 | PTEN | 5 |
chr10 | 89711806 | 89711936 | PTEN | 6 |
chr10 | 89717622 | 89717747 | PTEN | 7 |
chr10 | 89720778 | 89720902 | PTEN | 8 |
chr10 | 123256020 | 123256129 | FGFR2 | 13 |
chr10 | 123279495 | 123279622 | FGFR2 | 7 |
chr11 | 533800 | 533929 | HRAS | 3 |
chr11 | 534220 | 534349 | HRAS | 2 |
chr11 | 69456096 | 69456216 | CCND1 | 1 |
chr11 | 69458624 | 69458747 | CCND1 | 3 |
chr11 | 119103162 | 119103275 | CBL | 2 |
chr11 | 119148912 | 119149006 | CBL | 8 |
chr11 | 119149215 | 119149290 | CBL | 9 |
chr12 | 25380249 | 25380348 | KRAS | 3 |
chr12 | 25398183 | 25398310 | KRAS | 2 |
chr12 | 69210596 | 69210679 | MDM2 | 4 |
chr12 | 69233038 | 69233165 | MDM2 | 11 |
chr13 | 48881433 | 48881526 | RB1 | 2 |
chr13 | 48916793 | 48916902 | RB1 | 3 |
chr13 | 48923124 | 48923208 | RB1 | 6 |
chr13 | 48951050 | 48951160 | RB1 | 13 |
chr13 | 48954320 | 48954437 | RB1 | 16 |
chr13 | 48955427 | 48955539 | RB1 | 17 |
chr13 | 49027105 | 49027191 | RB1 | 18 |
chr13 | 49033834 | 49033935 | RB1 | 20 |
chr13 | 49037844 | 49037955 | RB1 | 21 |
chr13 | 49039144 | 49039221 | RB1 | 22 |
chr13 | 49039304 | 49039410 | RB1 | 23 |
chr14 | 36987081 | 36987213 | NKX-2.1 | 2 |
chr14 | 36988227 | 36988351 | NKX-2.1 | 1 |
chr14 | 105246470 | 105246589 | AKT1 | 3 |
chr17 | 7573886 | 7574019 | TP53 | 10 |
chr17 | 7576836 | 7576950 | TP53 | 9 |
chr17 | 7577028 | 7577157 | TP53 | 8 |
chr17 | 7577492 | 7577629 | TP53 | 7 |
chr17 | 7578180 | 7578289 | TP53 | 6 |
chr17 | 7578425 | 7578555 | TP53 | 5 |
chr17 | 7579278 | 7579397 | TP53 | 4 |
chr17 | 7579454 | 7579566 | TP53 | 4 |
chr17 | 37880169 | 37880287 | ERBB2 | 19 |
chr17 | 37880958 | 37881089 | ERBB2 | 20 |
chr18 | 48581196 | 48581323 | SMAD4 | 5 |
chr18 | 48584702 | 48584826 | SMAD4 | 7 |
chr18 | 48591813 | 48591934 | SMAD4 | 9 |
chr18 | 48604680 | 48604811 | SMAD4 | 12 |
chr19 | 1206977 | 1207113 | STK11 | 1 |
chr19 | 1218379 | 1218488 | STK11 | 2 |
chr19 | 1220390 | 1220504 | STK11 | 4 |
chr19 | 1220594 | 1220684 | STK11 | 5 |
chr19 | 1221205 | 1221340 | STK11 | 6 |
chr19 | 1223020 | 1223155 | STK11 | 8 |
chr19 | 10599879 | 10600011 | KEAP1 | 5 |
chr19 | 10600372 | 10600496 | KEAP1 | 4 |
chr19 | 10602263 | 10602390 | KEAP1 | 3 |
chr19 | 10602579 | 10602708 | KEAP1 | 3 |
chr19 | 10602796 | 10602912 | KEAP1 | 3 |
chr19 | 10610088 | 10610218 | KEAP1 | 2 |
chr19 | 10610289 | 10610416 | KEAP1 | 2 |
chr19 | 10610465 | 10610599 | KEAP1 | 2 |
chr19 | 11094812 | 11094945 | SMARCA4 | 2 |
chr19 | 11136088 | 11136220 | SMARCA4 | 22 |
chr19 | 11138426 | 11138556 | SMARCA4 | 23 |
chr19 | 11141448 | 11141561 | SMARCA4 | 25 |
chr19 | 11144042 | 11144179 | SMARCA4 | 26 |
chr19 | 30308024 | 30308156 | CCNE1 | 5 |
chr19 | 30313134 | 30313262 | CCNE1 | 10 |
chrX | 47028755 | 47028888 | RBM10 | 3 |
chrX | 47034396 | 47034523 | RBM10 | 5 |
chrX | 63411268 | 63411399 | FAM123B/AMER1 | 1 |
chrX | 63412836 | 63412964 | FAM123B/AMER1 | 1 |
Custom panel Cologne | ||||
chr1 | 115256352 | 115256453 | NRAS | 3 |
chr1 | 115256453 | 115256550 | NRAS | 3 |
chr1 | 115256550 | 115256672 | NRAS | 3 |
chr1 | 115258676 | 115258798 | NRAS | 2 |
chr1 | 162688829 | 162688951 | DDR2 | 3 |
chr1 | 162722872 | 162722995 | DDR2 | 4 |
chr1 | 162724359 | 162724466 | DDR2 | 5 |
chr1 | 162724466 | 162724586 | DDR2 | 5 |
chr1 | 162724586 | 162724687 | DDR2 | 5 |
chr1 | 162724850 | 162724967 | DDR2 | 6 |
chr1 | 162724967 | 162725094 | DDR2 | 6 |
chr1 | 162725447 | 162725572 | DDR2 | 7 |
chr1 | 162729566 | 162729694 | DDR2 | 8 |
chr1 | 162729681 | 162729782 | DDR2 | 8 |
chr1 | 162730973 | 162731107 | DDR2 | 9 |
chr1 | 162731107 | 162731197 | DDR2 | 9 |
chr1 | 162731197 | 162731276 | DDR2 | 9 |
chr1 | 162735765 | 162735879 | DDR2 | 10 |
chr1 | 162736904 | 162737029 | DDR2 | 11 |
chr1 | 162737029 | 162737154 | DDR2 | 11 |
chr1 | 162740090 | 162740201 | DDR2 | 12 |
chr1 | 162740201 | 162740327 | DDR2 | 12 |
chr1 | 162741756 | 162741887 | DDR2 | 13 |
chr1 | 162741887 | 162742002 | DDR2 | 13 |
chr1 | 162742002 | 162742088 | DDR2 | 13 |
chr1 | 162743204 | 162743301 | DDR2 | 14 |
chr1 | 162743301 | 162743421 | DDR2 | 14 |
chr1 | 162745384 | 162745513 | DDR2 | 15 |
chr1 | 162745513 | 162745634 | DDR2 | 15 |
chr1 | 162745915 | 162746038 | DDR2 | 16 |
chr1 | 162746038 | 162746162 | DDR2 | 16 |
chr1 | 162748317 | 162748432 | DDR2 | 17 |
chr1 | 162748432 | 162748519 | DDR2 | 17 |
chr1 | 162749866 | 162749977 | DDR2 | 18 |
chr1 | 162749977 | 162750066 | DDR2 | 18 |
chr2 | 29432650 | 29432776 | ALK | 25 |
chr2 | 29436843 | 29436974 | ALK | 24 |
chr2 | 29443565 | 29443688 | ALK | 23 |
chr2 | 29443688 | 29443772 | ALK | 23 |
chr2 | 29445200 | 29445332 | ALK | 22 |
chr2 | 29445369 | 29445489 | ALK | 21 |
chr3 | 41266072 | 41266193 | CTNNB1 | 3 |
chr3 | 178935940 | 178936023 | PIK3CA | 9 |
chr3 | 178936023 | 178936105 | PIK3CA | 9 |
chr3 | 178936092 | 178936180 | PIK3CA | 9 |
chr3 | 178951824 | 178951942 | PIK3CA | 20 |
chr3 | 178951942 | 178952063 | PIK3CA | 20 |
chr3 | 178952063 | 178952155 | PIK3CA | 20 |
chr7 | 55241596 | 55241679 | EGFR | 18 |
chr7 | 55241679 | 55241800 | EGFR | 18 |
chr7 | 55242411 | 55242539 | EGFR | 19 |
chr7 | 55248984 | 55249117 | EGFR | 20 |
chr7 | 55249117 | 55249200 | EGFR | 20 |
chr7 | 55259367 | 55259486 | EGFR | 21 |
chr7 | 55259484 | 55259567 | EGFR | 21 |
chr7 | 116411701 | 116411801 | cMET | intron 13/14 |
chr7 | 116411801 | 116411909 | cMET | 14 |
chr7 | 116411894 | 116411998 | cMET | intron 13/14 |
chr7 | 116411998 | 116412072 | cMET | 14 |
chr7 | 140453023 | 140453099 | BRAF | 15 |
chr7 | 140453099 | 140453224 | BRAF | 15 |
chr7 | 140481297 | 140481387 | BRAF | 11 |
chr7 | 140481387 | 140481511 | BRAF | 11 |
chr10 | 89624207 | 89624322 | PTEN | 1 |
chr10 | 89653745 | 89653817 | PTEN | 2 |
chr10 | 89653816 | 89653930 | PTEN | 2 |
chr10 | 89685258 | 89685374 | PTEN | 3 |
chr10 | 89690819 | 89690917 | PTEN | 4 |
chr10 | 89692713 | 89692819 | PTEN | 5 |
chr10 | 89692819 | 89692920 | PTEN | 5 |
chr10 | 89692920 | 89693032 | PTEN | 5 |
chr10 | 89711802 | 89711928 | PTEN | 6 |
chr10 | 89711917 | 89712018 | PTEN | 6 |
chr10 | 89717580 | 89717695 | PTEN | 7 |
chr10 | 89717694 | 89717792 | PTEN | 7 |
chr10 | 89720692 | 89720768 | PTEN | 8 |
chr10 | 89720769 | 89720842 | PTEN | 8 |
chr10 | 89724948 | 89725061 | PTEN | 9 |
chr10 | 89725058 | 89725147 | PTEN | 9 |
chr10 | 89725207 | 89725320 | PTEN | 9 |
chr12 | 25380167 | 25380240 | KRAS | 3 |
chr12 | 25380240 | 25380357 | KRAS | 3 |
chr12 | 25398183 | 25398304 | KRAS | 2 |
chr12 | 25398304 | 25398379 | KRAS | 2 |
chr14 | 105246406 | 105246502 | AKT1 | 4 |
chr14 | 105246500 | 105246583 | AKT1 | 4 |
chr15 | 66727356 | 66727487 | MAP2K1 | 2 |
chr15 | 66727487 | 66727602 | MAP2K1 | 2 |
chr17 | 7577017 | 7577142 | TP53 | 8 |
chr17 | 7577140 | 7577233 | TP53 | 8 |
chr17 | 7577392 | 7577509 | TP53 | 7 |
chr17 | 7577508 | 7577611 | TP53 | 7 |
chr17 | 7578141 | 7578234 | TP53 | 6 |
chr17 | 7578234 | 7578362 | TP53 | 6 |
chr17 | 7578310 | 7578425 | TP53 | 5 |
chr17 | 7578425 | 7578555 | TP53 | 5 |
chr17 | 7579278 | 7579385 | TP53 | 4 |
chr17 | 7579385 | 7579502 | TP53 | 4 |
chr17 | 7579502 | 7579590 | TP53 | 4 |
chr17 | 37880155 | 37880283 | HER2 | 19 |
chr17 | 37880960 | 37881074 | HER2 | 20 |
chr17 | 37881074 | 37881206 | HER2 | 20 |