Table 3.

Baseline Characteristics and Age-Adjusted ORs for a Decline of 5° or More in Average AVF over a 2-Year Period in the SEEDS

Variable	Loss of 5° or More, n = 138	No Loss (Less Than 5° Loss or Gain) n = 830 Base Outcome	Age–Adjusted OR (95% CI)	Age–Adjusted P Value
Demographics
Age mean (SD)	76.47 (4.78)	75.24 (5.09)
Sex, % (n)
Male	43.5 (60)	49.4 (410)	0.79 (0.55–1.13)	0.20
Race, % (n)
Black	12.3 (17)	9.6 (80)	1.49 (0.84–2.63)	0.17
Y of education, % (n)
>12 y	48.6 (67)	54.7 (454)	0.82 (0.57–1.17)	0.27
Baseline medical history, % (n)
Diabetes	16.7 (23)	15.4 (128)	1.12 (0.69–1.82)	0.653
Arthritis	54.4 (75)	57.4 (476)	0.89 (0.62–1.28)	0.54
History of stroke	15.9 (22)	7.1 (59)	2.39 (1.41–4.06)	0.001
Parkinson's disease	0.7 (1)	0.4 (3)
Pain score, mean (SD)	0.85 (1.06)	0.85 (1.04)	1.00 (0.84–1.19)	0.98
Depression score, mean (SD)	4.37 (3.57)	3.27 (3.35)	1.08 (1.03–1.13)	0.002
Baseline cognitive indicators
MMSE score, mean (SD)	28.29 (1.80)	28.62 (1.43)	0.89 (0.80–0.99)	0.04
Attention, mean (SD)	6.50 (2.28)	6.93 (2.29)	0.94 (0.87–1.02)	0.15
Trails A: per 5 s	52.14 (22.34)	44.89 (17.24)	1.09 (1.01–1.02)	<0.0001
Trails B: per 5 s	133.60 (70.27)	112.29 (58.06)	1.02 (1.01–1.03)	0.001
Baseline contrast sensitivity in better eye	35.28 (1.87)	35.52 (2.07)	0.97 (0.89–1.07)	0.56
Baseline log visual acuity per 1 line of visual loss	0.02 (−1.87–4.77)	−0.25 (−1.87–4.23)	1.19 (1.01–1.41)	0.03
Baseline visual field (center 20°)	0.44 (1.612)	0.16 (0.834)	1.19 (1.03–1.38)	0.02
Baseline average AVF, mean (SD)	15.33 (3.70)	13.65 (4.19)	1.13 (1.08–1.19)	<0.0001
Baseline horizontal AVF in degrees, mean (SD)	16.89 (3.79)	15.32 (4.65)
Baseline vertical AVF, mean (SD)	13.77 (4.78)	11.98 (4.85)