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. 2015 Sep 10;7(9):e322. doi: 10.7759/cureus.322

Table 3. Baseline characteristics of p16-positive subjects, by laterality of radiation.

Characteristic Unilateral RT (n=53) Bilateral RT (n=89) p-value
 Mean age at diagnosis 55.2 56.0 0.65
Gender 0.09
Male 43 (81%) 74 (83%)  
Female 10 (19%) 15 (17%)  
T Stage < 0.01
T1 22 (42%) 22 (25%)  
T2 28 (53%) 39 (44%)  
T3 3 (6%) 21 (24%)  
T4 0 8 (8%)  
N Stage < 0.01
N0 15 (28%) 11 (12%)  
N1 18 (34%) 8 (9%)  
N2a 7 (13%) 9 (10%)  
N2b 11 (21%) 36 (40%)  
N2c 0 12 (14%)  
N3 2 (4%) 13 (15%)  
Stage < 0.01
I 1 (2%) 2 (2%)  
II 13 (25%) 5 (6%)  
III 19 (36%) 9 (10%)  
IVA 18 (34%) 60 (67%)  
IVB 2 (4%) 13 (15%)  
Smoking 0.03
Current/quit less than 1 year 13 (25%) 29 (33%)  
Former (quit more than 1 year) 28 (53%) 27 (30%)  
Never 12 (23%) 33 (37%)  
Radiation
< 60 Gy 35 (66%) 31 (35%) < 0.01
61-70 Gy 18 (34%) 58 (65%)
RT alone 42 (79%) 41 (46%) <0.01
CRT 11 (21%) 48 (54%)
Chemotherapy 0.30
Cisplatin-based 19 (91%) 37 (77%)  
Carboplatin-based 1 (9%) 11 (23%)  
Surgery 0.29
None 51 (96%) 77 (87%)  
Primary resection 0 1 (1%)  
Post-RT primary and UND 0 1 (1%)  
Post-RT UND 2 (4%) 1 0 (11%)