Table 6.

Description of cases in which treatment failure occurred.

Age	Host status	Etiology	Site	Anatomic nature	Risk factors	Management strategy	Treatment
44	B	Contiguous post-traumatic	Tibia	IV	Compliance and motivation	Curative	Wide resection, Masquelet bone transport
34	C	Contiguous post-traumatic	Ankle	IV	HIV infection (CD4 <350 cells/mm3), smoking, joint involved	Alternative	Patient refused amputation, marginal debridement and acute shortening
25	C	Contiguous post-traumatic	Tibia	IV	HIV infection (CD4 <350 cells/mm3)	Alternative	Circular fixation, fibula osteotomy, CSATa
30	C	Contiguous post-traumatic	Midfoot	IV	Poor soft tissue, joint involved, foot, local extent	Palliative	CSATa
49	C	Contiguous post-traumatic	Tibia	III	HIV infection (CD4 <350 cells/mm3), poor soft tissue, local extent, debridement will result in instability	Palliative	CSATa
26	B	Contiguous post-traumatic	Proximal tibia	IV	Failed reconstruction elsewhere, joint involved, poor soft tissues	Curative	Wide resection, classic Masquelet
45	C	Contiguous post-operative	Proximal femur	III	Chronic venous insufficiency, joint involved, local extent, debridement will result in instability	Palliative	CSATa
65	C	Contiguous post-operative	Femur	III	Ischemic heart disease, smoker, diabetes mellitus (HbA1c > 8), age	Palliative	CSATa
46	B	Hematogenous	Pelvis	III	Smoking, local extent, pelvis	Curative	Marginal resection, PMMA beads
38	C	Contiguous post-operative	Humerus	IV	HIV infection (CD4<350cells/mm3), adjacent joint stiffness, local extent, diabetes mellitus	Palliative	CSATa
48	C	Contiguous post-traumatic	Proximal tibia	III	HIV infection (CD4 <350 cells/mm3), smoking, local extent, poor soft tissues	Palliative	CSATa

^aChronic suppressive antibiotic therapy.