Table 1.
MBL2 Diplotypes in Children With Invasive Meningococcal Disease and Controls
| Group | Status | Normal Diplotypes: YA/YA, XA/YA (%) | Intermediate Diplotypes: XA/XA, YA/YO (%) | Defective Diplotypes: XA/YO, YO/YO (%) | Total, (%) | P Valuea | Odds Ratio (95% Confidence Interval)b |
|---|---|---|---|---|---|---|---|
| Meningitis | Control | 211 (55) | 100 (26) | 71 (19) | 382 | .15 | 0.69 (.47–1.02) |
| Case | 219 (57) | 115 (30) | 53 (14) | 387 | |||
| Bacteremia | Control | 129 (50) | 82 (32) | 49 (19) | 260 | .62 | 0.84 (.53–1.32) |
| Case | 141 (54) | 79 (30) | 43 (16) | 263 | |||
| Combined | Control | 340 (53) | 182 (28) | 120 (19) | 642 | .17 | 0.75 (.56–1.01) |
| Case | 360 (55) | 194 (30) | 96 (15) | 650 |
a 2 × 3 χ2 test, degrees of freedom = 2.
b Comparison of defective diplotypes vs intermediate combined with normal diplotypes and adjusted for sex.