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. 2015 Oct 13;6:1569. doi: 10.3389/fpsyg.2015.01569

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Copyright © 2015 Jiang, Shang and Su.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Linkage disequilibrium (LD) pattern of the seven catechol-O-methyltransferase (COMT) single nucleotide polymorphisms (SNPs) analyzed in the present study. The upper panel shows the location of seven polymorphisms in COMT gene and the lower panel presents the output of Haploview. Numbers in each square present the r² value of a pairwise LD relationship between any two SNPs. Two haplotype blocks were defined using the solid spine of LD algorithm.