Table 2.

Mixed Effect Longitudinal Models with AES Sub-Scale Scores as Dependent Variables

Dependent Variable	Retained Predictors	Effect (β)	95% CI	p	% Var Acct F	% Var Acct F+R
AES-S	Male Sex	−3.09‡	(−5.74, −0.44)	0.02	7.6	85.8
	Year in Study	−0.85	(−1.7347, 0.03623)	0.06
AES-I	Baseline Diagnosis MCI	−7.60‡	(−11.61, −3.60)	0.0003	17.6	83.6
	Year in Study	−2.61	(−3.73, −1.49)	<0.0001
AES-C	Baseline Diagnosis MCI	−7.28‡	(−11.27, −3.30)	0.0005	23.3	85.6
	Male Sex	−0.84‡	(−4.39, 2.72)	0.64
	Year in Study	−3.05	(−4.18, −1.92)	0.002
	Year in Study X Male Sex	−2.89	(−4.87, −0.92)	0.005

X denotes an interaction.

Apathy Evaluation Scale, subject-reported sub-scale (AES-S); Apathy Evaluation Scale, informant-reported sub-scale (AES-I); Apathy Evaluation Scale, clinician-reported sub-scale (AES-C); confidence interval (CI); percent variance in dependent variable accounted for by fixed effects of model (% Var Acct F); percent variance in dependent variable accounted for by fixed and random effects of model (% Var Acct F+R); mild cognitive impairment (MCI)

^‡β for a categorical predictor is the estimated difference in adjusted means for the categories.