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. 2015 Oct 13;5:15045. doi: 10.1038/srep15045

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UCB induced oxidative stress and lysosomal alkalinisation as assessed by (A) G6PDH activity (B) GGT activity and (C) Lysosomal stability. Cytotoxic properties of UCB as determined by (D) LDH leakage (E) MTT cell viability assay and (F) Flow cytometric analysis of macrophages mediated engulfment of calcein-labeled control and UCB (100 μM) treated platelets. Values are presented as mean ± SEM (n = 5), expressed as percentage decrease in (C) LysoSensor Green DND-189 fluorescence. *p < 0.05, **p < 0.01, ***p < 0.001; significant compared to control platelets.