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Sarcoplasmic reticulum Ca2+ storage is similar in collagen-induced arthritis (CIA) and control fibres. (A) Typical example (120 Hz stimulation frequency, 350 ms train duration) of [Ca2+]i (upper panel) and specific force (lower panel) in the presence (---) or absence (—) of caffeine (5 mM, 2 min exposure). Mean values (±SEM, n=6) of [Ca2+]i (B) and specific force (C) in the presence or absence of caffeine in CIA and control FDB fibres. *p<0.05, **p<0.001 versus controls.
