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Serum IgG4 in patients with IgG4-RD. (A) IgG4 concentrations and the IgG4/IgG ratio at the time of diagnosis are summarized. Gray circles indicate 198 patients (84%) having either IgG4 >270 mg/dL or IgG4 135–270 mg/dL and IgG4/IgG >10%. (B) Correlation between IgG4 and IgG concentrations in IgG4-RD patients. The black line indicates the 10% IgG4/IgG ratio. Dotted lines are for 20% and 30%. Ig = immunoglobulin, IgG4-RD = IgG4-related disease.
